There isn't a simple answer to this. A lot of factors have to be considered.
Just to take a few, and using an extreme example, Large Truck Tyres on HGV's.
A typical Articulated Truck and Trailer on long haul will exceed 100,000 km per tyre all round on a 6x2 tractor unit.
Now take a 6x2 Rigid Refuse Truck on household collections and you may drop to half that.
Make it a 6x4 (double drive) on Bulk Animal Feed delivery in mid Wales and that can drop to 20,000 km.
So it is all down to route, road conditions, power steering, stop/start journeys, power to weight and of course Driving Style.
If you look across the typical Land Rover range and evolution from Defender on Cross Ply Tyres to Discovery, Freelander, Range Rover not to mention all the new 'Exotic' stuff, tyres have many applications and most are now Radial which will give better performance.
In addition 4WD comes in many forms and some systems are kinder on the tyres.
There is a argument for rotating front & rear to improve overall mileage but, as you pointed out, you are likely to have to fit 4 then.
One final point, it is important to fit the tyres with the best cornering force on the rear. This applies to AWD, FWD or RWD.
To have new tyres on the front of a Front Wheel Drive Vehicle and minimal tread on the rears can result in a dangerous oversteer condition.